王子醫師部落格

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國人因服用腎毒性藥物引發腎功能不全，十分普遍且日益嚴重，根據【現代醫療診斷與治療】教科書中表列:

一、引發急性腎小管壞死之藥物 (Causes of acute tubular necrosis)

(1) Aminoglycosides

(2) Amphotericin B

(3) Radiographic contrast medium

(4) Cyclisporine

(5) Antineoplastics

(6) Organic solvent

(7) Heavy metals, etc. Hg, As, Cd

二、引發腎小管間隙組織腎炎之藥物 (Causes of tubulointerstitial nephritis)

1. Antibiotics

(1) Beta-lactam antibiotics: methicillin, penicillin, ampicillin, cephalosporins

(2) Ciprofloxacin

(3) Erythromycin

(4) Sulfonamides

(5) Tetracycline

(6) Vancomycin

(7) Trimethoprim-sulfamethoxazole

(8) Ethambutol

(9) Rifampin

2. Nonsteroidal anti-inflammatory drugs (NSAID)

3.  Diuretics

(1) Thiazides

(2) Furosemide

4. Miscellaneous

(1) Allopurinol

(2) Cimetidine

(3) Phenytoin

出處: 2014 Current medical diagnosis & treatment P871-899